Mitochondrial
|
Immunofluorescence Patterns Associated with Disorders of:
|
|
|
Add this site to favorites
|
Autoimmune liver disease: Mitochondrial antibodies
| Mitochondrial antibodies (AMA) |
 |
 |
 |
|
Stomach |
Liver |
Kidney tubules |
|
Parietal cells |
Chief cells |
Hepatocytes |
Proximal |
Distal |
| ++ |
+/- |
++ |
++ |
+++ |
|
Rodent stomach: Cytoplasm of
gastric parietal cells is shown in green with black unstained nuclei. |
Rodent liver showing granular
staining of the cytoplasm with red nuclei. |
In contrast to the LKM antibody,
AMA stains cytoplasm of both the proximal and distal renal tubules. Centre
is unstained glomerulus. |
| Anti-mitochondrial
antibodies are strongly associated with Primary biliary cirrohsis. |
|
|
|
|